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Renaliz-67


                  6                              DÜNDEN BUGÜNE PERİTON DİYALİZİ



                                    Prof. Dr. Ayşe BALAT
                                    İstanbul Aydın Üniversitesi Tıp Fakültesi / Çocuk Nefroloji & Romatoloji BD

                 Diyabete Bağlı Böbrek Hastalığı
               Dünden Bugüne Periton Diyalizi
                                                                        Diyaliz Nedir?                            • %XUXQ NDQDPDVÖ YFXGXQ ]DUDUOÖ PDGGHOHUGHQ
                                                                                                                       temizlenmeVL LoLQ ID\GDOÖGÖU

                                                          • <DUÖ JHoLUJHQ ELU ]DU DUDFÖOÖùÖ\OD NDQ LOH X\JXQ GL\DOL] VROV\RQX   • $WHü RODQ ELULQGH VDùÖUOÖN  EXUXQ NDQDPDVÖ YH\D
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                     DùÖ]GD DFÖPVÖ WDW YDUVD YFXGXQ WHPL]OHQPH\H LKWL\DFÖ YDUGÖU                       • +LSRNUDW- Galen; SDUDVHQWH]
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                       gGHPOL ELU KDVWDQÖQ NDUÖQ GDPDUODUÖQGDNL VX GLUHQH HGLOLUVH                      • Paul of Aegina    \\ - |]HO ELU ELVWUL icat etti
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                       .|W üH\OHUL DWPDN LoLQ .$1$                                       3OHYUD
                       *LULüLQL HQJHOOHPHN LoLQ $d .$/    Diyare
                       .DODQÖQÖ DWPDN LoLQ $/77$1-h677(1 d,.$5                                                                  'LDPDQGRSRXORV 7  Am J 1HSKURO 1997
                                    'LDPDQGRSRXORV 7  Am J 1HSKURO 1997                     ÖDEM



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                        2. Purgatif                                                                                RUJDQODUÖQ HWUDIÖQÖQ ELU NHVH WDUDIÖQGDQ
                           .HQGL LGUDUÖQÖ LoPHN                            ¶·1DVÖO NL \DùPXU oRN \DùDUVD \HU\]   VDUÖOGÖùÖQÖ IDUNHWWL
                           *|EHN DOWÖQGDQ   SDUPDN X]DNOÖNWD LQVL]\RQ «    ÖVODQÖU  ER]XOXU  IRQNVL\RQ J|UHPH] KDOH   • *DOHQ YH DQWLN oDùÖQ |QGH JHOHQ SHN oRN
                                                                           gelir.                                  KHNLPL  \DUDOÖ JODG\DW|UOHULQ DoÖN NDUQÖQGDNL
                      ¶·«$OWÖQ  JPü YH\D EURQ] NDQO \HUOHüWLU  +DVWDQÖQ   &HQQHWWH RODùDQGÖüÖ ELU \DùÖü ROXUVD    SHULWRQX J|]OHPOHGL
                      QDE]ÖQD EDN  ]D\ÖIVD NDQO oÖNDU  üDUDS \D GD EH\D]   \HU\]QGHNL LQVDQODU GD HWNLOHQLU YH   • (UNHQ G|QHPGHNL DQDWRPLVWOHU YH
                      \XPXUWD\D EDWÖUÖOPÖü ELU SDQVXPDQ \DS  +DVWD\Ö \DWÖU    EX VX RQODUÖQ LoLQH G|NOU«··       FHUUDKODU  SHULWRQHDO PHPEUDQÖQ JHQLüOLùLQL
             úEQ-L 6LQD   WDYXN VX\X oRUED YH\D NROD\ KD]PHGHFHùL JÖGDODU YHU                                      \]H\OHULQL YH HNOHULQL LVLPOHQGLUGL  DQFDN
                                                                                                                   LüOHYLQGH \D GD LQFH \DSÖVÖQGD D\UÖQWÖ
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                         ID]OD VX oHN  EXQX   YH ]HULQGH WHNUDUOD«··                                              YHUPHGL
                              «,QWHUPLWDQW Diyaliz»                                                    1550-0ÖVÖU SDSLUVOHUL  • +FUHQLQ WDQÖPODQPDVÖQGDQ VRQUD
                                                                                  'LDPDQGRSRXORV 7  Am J 1HSKURO 1997   DQDWRPLVWOHULQ LOJLVLQL oHNPH\H EDüODGÖ«
                                   'LDPDQGRSRXORV 7  Am J 1HSKURO 1997

                   1743ĺúON SDUDVHQWH] YH SHULWRQHDO ODYDM
                                                           • 1854- *UDKDP  VÖùÖU PHVDQHVL NXOODQDUDN NROORLGOHULQ YH NULVWDORLGOHULQ   • 1862-Von 5HFNOLQJKDXVVHQ LON NH] SHULWRQXQ PDNURVNRELN YH KFUHVHO
                                                            D\UÖODELOGLùLQL J|VWHUGL
                                                           • “2]PRWLN *oµ RODUDN DGODQGÖUÖODQ ELU VUHFL WDQÖPODGÖ YH ´oHPEHUµ WLSL   DQDWRPLVLQL WDQÖPODGÖ   ¶·SHULWRQ VHPLSHUPHDEOH ELU PHPEUDQGÖU··
                                       (üLW PLNWDUODUGD     ELU GL\DOL]|U JHOLüWLUGL                    • 1877-G Wegner ;
                                    Burgundy üDUDEÖ + %ULVWRO VX\X    • +D\YDQ GRNXVXQXQ  PROHNOOHULQ VHoLFL RODUDN JHoHELOGLùL ELU ¶·\DUÖ
                                                            JHoLUJHQ ]DU·· RODUDN NXOODQÖODELOHFHùLQL EHOLUWWL        'HùLüLN ÖVÖODUGDNL VÖYÖ SHULWRQD YHULOLQFH YFXW ÖVÖVÖ GHùLüPHNWHGLU
                                                                                                           <RùXQ GHNVWUR]  JOLVHULQ YHULOLQFH SHULWRQGDQ JHOHQ VÖYÖ DUWPDNWDGÖU  LON 8)
                                       7ROHUDQV N|W  DVLW
                                       ROXüXPXQGD azalma     'Öü GQ\D LOH YFXW DUDVÖQGD \DUÖ JHoLUJHQ ELU ]DU YDUGÖU    • 1894-6WDUOLQJ YH 7XEE\; 3HULWRQ YH SOHYUDGDQ LNL \|QO PROHNOHU JHoLü
                                                                                                         ROPDNWDGÖU  ú]RWRQLN VÖYÖ JHoLüL KÖ]OÖ  VHUXP JHoLüL \DYDüWÖU
                                     ûDUDS PLNWDUÖ DUWÖUÖOGÖ              ¶·'L\DOL]··

                                       ú<ú/(û0(                                   *UDKDP 7  3KLORV 7UDQV 6oc /RQG 1854



          •     \]\ÖOÖQ LON oH\UHùLQGH PD LoLQ IL]\RORMLN WHPHO ROXüWXUXOGX     • *Peritoneal PHPEUDQ Na YH GLùHU PLQHUDOOHUH NDUüÖ JHoLUJHQGLU
                                                                                                       • 1923- Georg Ganter (8QLY. of :XU]EXUJ - LQVDQODUGD LON NH] 6)
          • 6ÖYÖODUÖQ RVPRODOLWHVL ile SHULWRQHDO XOWUDILOWUDV\RQ  SHULWRQHDO NDYLWH ile   •   .DUÖQ |Q GXYDUÖQD ÖVÖ X\JXODQPDVÖ SHULWRQ ERüOXùX LOH NDQ DUDVÖQGDNL PDGGH   NXOODQDUDN SHULWRQHDO ODYDM WHNQLùLQL D\UÖQWÖODUÖ\OD WDQÖPODGÖ
           LQWUDYDVNOHU NRPSDUWPDQ DUDVÖQGDNL NoN PROHNOOHULQ DEVRUSVL\RQX YH LNL   JHoLüLQL DUWÖUPDNWDGÖU   |QHULOHUGH EXOXQGX  ([SHULPHQWDO oDOÖüPD 6) LOH SHULWRQHDO
           \|QO DNÖüÖ DUDVÖQGDNL LOLüNL YXUJXODQGÖ                                                     GHùLüLP VUHVL 2-  VDDWWLU
                                                         •    %X DUWÖüWDQ YD]RGLODWDV\RQ VRUXPOXGXU    • 1923-      $%' YH $OPDQ\D ¶·úQWHUPLWWHQW PD··
          • 1918- 'DPDU \ROX EXOXQDPD\DQ DùÖU GHKLGUDWH oRFXNODUD LQWUDSHULWRQHDO VÖYÖ                 • 1927- H. +HXVVHU YH H. Werder  &ÖYD ]HKLUOHQPHVL VRQXFX ABY
           X\JXODPDVÖ  SHULWRQ PHPEUDQÖQÖQ WHGDYL DPDoOÖ LON NXOODQÖPÖ    • 1922-Putnam;  +D\YDQ oDOÖüPDODUÖ- Diyaliz PHPEUDQÖ RODUDN  ¶·\DüD\DQ SHULWRQ··   JHOLüHQ   KDVWD\D ¶·FRQWLQXRXV IORZ 3'··  LNL NDWHWHU NXOODQDUDN
                                                         ¶·3OD]PD YH SHULWRQHDO VÖYÖ DUDVÖQGD SDVLI JHoLüL VDùOD\DQ R]PRWLN ELU GHQJH YDUGÖU··
          •      GH  infüzyon RVPRODOLWHVLQGHQ EDùÖPVÖ] RODUDN SHULWRQD YHULOHQ VÖYÖQÖQ                   UH G]H\L D]DOPDVÖQD UDùPHQ KDVWDODU ND\EHGLOGL   'U  *HRUJ *DQWHU
           ¶·   VDDW LoLQGH WDPDPHQ HPLOGLùL·· EHOLUWLOGL                          *Orlow WN. $UFK f 3K\V Pflüger 1895   • 1934-5RVHQDN  úON NH] R]PRWLN DMDQ RODUDN ¶·JOXNR]··X NXOODQDUDN
                                                                               **.ODSS R. Mitt *UHQ]JHE der Med u &KLU 1902
                                     /HDWKHV JB  6WDUOLQJ EH. J 3K\VLRO 1895         ***&ODUN AJ. J 3KDUPDFRO 1921   D\QÖ WHNQLùL GHQHGL  UH G]H\L D]DOGÖ DPD NOLQLN \LQH EDüDUÖVÖ]GÖ
                               +DPEXUJHU HJ. $UFKLY f 3K\V du %RLV-Reymond 1895       Putnam 7-. Am J 3K\VLRO 1922   • 1938- 5KRDGV ELNDUERQDW GHVWHùL LoLQ ODNWDW HNOHQHELOHFHùLQL
                                      &XQQLQJKDP 56. Am J 3K\VLRO 1920                3XWQDP 7J. Am J 3K\VLRO 1923
                                   6FKHFKWHU AJ YH DUN  Am J 'LV &KLOG 1933                             EHOLUWWL
                                                                                                                                       *DQWHU *   0XQFK Med :VFKU 1923
                                  *%ODFNIDQ KD  Maxcy .). Am J 'LV &KLOG 1918                                                      +HXVVHU +  :HUGHU +  %UXQ·V Beitr /LQ &KLU 1927
                                  *:HLQEHUJ M. =WVFKU f .LQGHUKHLONXQGH 1921                                                         %DOi]V -  5RVHQDN 6  :LHQ Klin :VFKU 1934
                                                                                                                                        5KRDGV -(  $P - 0HG 6FL 1938


                   1946-3'·QLQ LON EDüDUÖOÖ NXOODQÖPÖ            .RPSOLNDV\RQODU  7HNQLN VRUXQODU«
                                                                                                        • *Boen SHULWRQHDO diyalizat LoHULùLQLQ IRUPOQ ROXüWXUGX
            1946- -  )LQH                                 • 1950- +DQJL WHNQLN  3HULWRQD XODüÖP \ROX" Diyalizat" $NÖP KÖ]Ö"    $VHWDW     mEq /
            $ 6HOLJPDQ  +  )UDQN                          • Peritonal ODYDM VUHNOL DNÖü KDOLQGH PL ROPDOÖ (LNL NDWHWHU ile    Na : 130-140 mEq /
             %RVWRQ   R. Reid                             • AUDOÖNOÖ PÖ ROPDOÖ (infüzyon YH drenaj LoLQ D\QÖ NDWHWHU NXOODQÖODUDN     *OXNR]: 1.5-  J G/
             úQJLOWHUH  - 2. Dünya
            VDYDüÖ VRQUDVÖ  'HYDPOÖ                       • Hedef  ¶·(n GüN VÖ]ÖQWÖ YH SHULWRQLW RUDQÖ··    • %X IRUPO \ÖOODUFD DVHWDWÖQ \HULQL ODNWDW DOÖQFD\D NDGDU NXOODQÖOGÖ
            PD LOH G]HOHQ LON ABY                        • $UWKXU *UROOPDQ ÖQ oDOÖüPDODUÖQGDQ VRQUD PD VROV\RQX SHULWRQ
            ROJXODUÖ ELOGLULOGL                           ERüOXùXQGD EHOOL ELU VUH EÖUDNÖOPD\D EDüODQGÖ

                                                                                                                             *Boen 67  3HULWRQHDO GLDO\VLV  7KHVLV  $PVWHUGDP
                                  )UDQN +$  6HOLJPDQ +$  )LQH J. JAMA 1946                                                   7KH 1HWKHUODQGV  8QLYHUVLW\ RI $PVWHUGDP
                                    Reid 5  Penfold JB  -RQHV RN. /DQFHW 1946    Grollman $  7XUQHU /%  0DFOHDQ -$  $UFK ,QWHUQ 0HG
                                    $EERWW :(  6KHD 3  $P - 0HG 6FL 1946


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